| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1977440 | Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology | 2010 | 6 Pages |
The large use of tetrabromobisphenol A (B4BPA) in common products (plastics, electric and electronic equipments) has raised concern about its ecotoxicity. Physical and bio-degradations may lead to the formation of tetrabromobisphenol A derivatives like tri- (B3BPA), di- (B2BPA), monobromobisphenol A (B1BPA) and bisphenol A (BPA). However, little is known about the toxicity of these brominated derivatives. An appraisal on the ecotoxicity of B4BPA and its derivatives was carried out with several bioassays representing organisms (bacteria, algae, micro-invertebrates and fish) of different taxonomic groups present in aquatic ecosystems. Endpoint values showed that B4BPA was significantly less toxic than the other chemicals when tested with the Microtox and algal asssays. A similar trend was observed with other bioassays for BPA. One of the brominated derivatives was particularly toxic: B2BPA. The LuminoTox assay and the rainbow trout hepatocytes assay reported the most significant toxicity for this derivative. Its toxicity was also significantly higher than the other compounds barring B3BPA when tested with the micro-crustacean test.
