Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1979061 | Current Opinion in Structural Biology | 2013 | 9 Pages |
Abstract
⺠The complete subunit architecture of the proteasome regulatory particle is now known. ⺠Technical hurdles still challenge cryoEM structure determination of the proteasome. ⺠The proteasomal lid undergoes dramatic conformational movements during assembly. ⺠A model for substrate processing emerges, based on recent cryoEM reconstructions.
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Authors
Gabriel C Lander, Andreas Martin, Eva Nogales,