Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1979090 | Current Opinion in Structural Biology | 2012 | 11 Pages |
Abstract
⺠Structural networks are more informative than classical 'nodes-and-edges' networks. ⺠Structural networks differentiate between competitive and simultaneous binding. ⺠Structural networks can help drug design and may forecast some side effects. ⺠We outline how to construct structural networks on a large scale using PRISM. ⺠We construct the structural network of ERK proteins in the MAPK signaling pathway.
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Authors
Guray Kuzu, Ozlem Keskin, Attila Gursoy, Ruth Nussinov,