Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1979212 | Current Opinion in Structural Biology | 2012 | 9 Pages |
Abstract
⺠We review recent literature on coupled protein folding and binding reactions. ⺠We describe different kinetic mechanisms for folding coupled to binding. ⺠We discuss their consequences on the observed folding/association kinetics. ⺠We suggest experiments that can discriminate between different mechanisms. ⺠Experimental results on folding coupled to binding reactions are discussed.
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Authors
Thomas Kiefhaber, Annett Bachmann, Kristine Steen Jensen,