| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1979220 | Current Opinion in Structural Biology | 2012 | 8 Pages |
Abstract
⺠DNA unzipping reveals the detailed histone-DNA interactions within a nucleosome. ⺠A novel nucleosome disassembly intermediate is observed using smFRET. ⺠Distinct PTMs in a nucleosome separately regulate unwrapping rates and disassembly. ⺠Chromatin higher order structures are identified for various linker DNA lengths. ⺠Pol II may transcribe through the nucleosome using a Brownian ratchet mechanism.
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Authors
Jessica L Killian, Ming Li, Maxim Y Sheinin, Michelle D Wang,