| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1979288 | Current Opinion in Structural Biology | 2009 | 7 Pages |
Abstract
The modulation of enzyme function is a key regulatory feature of biological systems. The ability to engineer synthetic enzymes that can be controlled by any arbitrary signal would enable a wide array of sensing applications and therapeutics and provide us with powerful tools for the basic study of biology. Here several recent advances in the engineering of switchable enzymes through domain fusion are discussed.
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Authors
Marc Ostermeier,