| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1979340 | Current Opinion in Structural Biology | 2011 | 6 Pages |
Abstract
⺠Last four years, several inactive-state GPCR structures have been solved. ⺠Active-state structures may be unstable without a native signaling partner. ⺠Nanobodies act as surrogates of GPCR signaling partners. ⺠Nanobody 80 has G protein-like properties and stabilizes an agonist activated state of the β2AR.
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Authors
Jan Steyaert, Brian K Kobilka,