Article ID Journal Published Year Pages File Type
1979360 Current Opinion in Structural Biology 2009 8 Pages PDF
Abstract

Magnetic traps provide a simple technique to pull and twist a variety of biomolecules and monitor the resulting change in extension. They have been used with great success to investigate the interaction of stretched and supercoiled DNA and DNA fibers (e.g. chromatin) with a great variety of enzymes. In this small review we will address their recent use in the study of topoisomerases, gyrase, DNA translocases and various structural proteins.

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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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