| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1979370 | Current Opinion in Structural Biology | 2012 | 9 Pages |
Abstract
⺠PARP1 recognizes DNA strand breaks through substrate-assisted dimerization. ⺠PARP1 ZFIII and WGR domains link DNA break recognition to enzyme activation. ⺠Tankyrase-dependent PARylation regulates Wnt signalling and Cherubism syndrome.
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Authors
Markus Hassler, Andreas G Ladurner,