| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1979399 | Current Opinion in Structural Biology | 2009 | 6 Pages |
Abstract
Proteins in their evolution appear to follow several discrete stages, which is reflected in their modular organization. The sequences of the protein modules are highly variable while their functions and structures are rather conserved. The relatedness of the variable sequences is well represented by the networks in natural protein sequence space that also suggests evolutionary connections.
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Authors
Edward N Trifonov, Zakharia M Frenkel,