Article ID Journal Published Year Pages File Type
1979551 Current Opinion in Structural Biology 2008 9 Pages PDF
Abstract

ATP-dependent proteases control diverse cellular processes by degrading specific regulatory proteins. Recent work has shown that protein substrates are specifically transferred to ATP-dependent proteases through different routes. These routes can function in parallel or independently. In all of these targeting mechanisms, it can be useful to separate two steps: substrate binding to the protease and initiation of degradation.

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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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