Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1979721 | Current Opinion in Structural Biology | 2007 | 6 Pages |
Abstract
NMR has had considerable impact in enzymology, probing evidence for ionization states, conformational ‘strain’, compressed interactions, electronically unusual species, and conformational dynamics of enzymes. Solid-state NMR is becoming increasingly important in studying enzymes because of a number of recent tools for analysis of proteins by SSNMR, and because of the growing ability to isolate the species of interest for analysis. Here, we review recent studies of a Michaelis complex, of the dynamic functioning of membrane-associated enzymes, and initial studies of several enzymes with redox-active and paramagnetic centers.
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Authors
Ann McDermott, Tatyana Polenova,