| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1979764 | Current Opinion in Structural Biology | 2008 | 7 Pages |
Abstract
Aquaporins (AQPs) are a family of ubiquitous membrane channels that conduct water and solutes across membranes. This review focuses on AQP0 and AQP4, which in addition to forming water channels also appear to play a role in cell adhesion. We discuss the recently determined structures of the membrane junctions mediated by these two AQPs, the mechanisms that regulate junction formation, and evidence that supports a role for AQP0 and AQP4 in cell adhesion.
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Authors
Andreas Engel, Yoshinori Fujiyoshi, Tamir Gonen, Thomas Walz,