Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1979834 | Current Opinion in Structural Biology | 2006 | 7 Pages |
Abstract
Structural genomics (also known as structural proteomics) aims to generate accurate three-dimensional models for all folded, globular proteins and domains in the protein universe to understand the relationship between protein sequence, structure and function. NMR spectroscopy of small (<20Â kDa) proteins has been used successfully within several large-scale structural genomics projects for more than six years now. Recent advances coming from traditional NMR structural biology laboratories as well as large scale centers and consortia using NMR for structural genomics promise to facilitate NMR analysis making it even a more efficient and increasingly automated procedure.
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Authors
Adelinda Yee, Aleksandras Gutmanas, Cheryl H Arrowsmith,