Article ID Journal Published Year Pages File Type
1980304 DNA Repair 2013 12 Pages PDF
Abstract
► WRN and BLM human RECQ helicases contribute additively to fork progression during normal replication. ► After short-term HU block, fork restart requires non-additive contributions of BLM, WRN, and RAD51 that do not involve protection from DSBs. ► BLM but not WRN is required for timely G2/M transition after short-term HU block. ► Human fibroblasts appear to replace or degrade some of the DNA synthesized by recovering forks during the first hour after release from HU.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , , ,