Article ID Journal Published Year Pages File Type
1980312 DNA Repair 2011 10 Pages PDF
Abstract
► MutS complexes are required for the activation of the Fanconi Anemia pathway. ► MSH2 but not MLH1 depleted cells are sensitive to DNA crosslinking agents. ► MSH2 is required for the chromatin recruitment of the FA core complex upon DNA damage. ► MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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