Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1980312 | DNA Repair | 2011 | 10 Pages |
Abstract
⺠MutS complexes are required for the activation of the Fanconi Anemia pathway. ⺠MSH2 but not MLH1 depleted cells are sensitive to DNA crosslinking agents. ⺠MSH2 is required for the chromatin recruitment of the FA core complex upon DNA damage. ⺠MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway.
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Authors
Min Huang, Richard Kennedy, Abdullah M. Ali, Lisa A. Moreau, Amom Ruhikanta Meetei, Alan D. D'Andrea, Clark C. Chen,