Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1980316 | DNA Repair | 2011 | 9 Pages |
Abstract
⺠The Siz SUMO ligases participate in nucleotide excision repair in yeast. ⺠Several NER factors are sumoylated, including Rad4, Rad16, Rad7, Rad1, and Rad10. ⺠SUMO attachment to Rad16 is not required for UV resistance or repair of DNA lesions. ⺠SUMO-modified Rad4 accumulates in NER pathway mutants that block downstream of Rad4. ⺠Rad4 may become sumoylated at a specific point in its functional cycle.
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Authors
Hannah R. Silver, Jared A. Nissley, Simon H. Reed, Ya-Ming Hou, Erica S. Johnson,