Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1980353 | DNA Repair | 2011 | 8 Pages |
Abstract
⺠Sodium butyrate increases the radiosensitivity of HeLa cells. ⺠Sodium butyrate does not abrogate the gamma-radiation imposed G2 cell cycle arrest. ⺠Sodium butyrate obstructs both NHEJ and HR. ⺠A suggestion is made that an early step in DNA double strand breaks repair is a deacetylation of core histones and compaction of chromatin structure to keep the DNA ends close to each other.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Miglena Koprinarova, Peter Botev, George Russev,