| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1980387 | DNA Repair | 2012 | 9 Pages |
Abstract
⺠Down-regulation of filamin-A impairs DNA repair efficiency. ⺠Filamin-A expression level reversely correlates with drug sensitivity. ⺠Inhibition of filamin-A sensitizes melanoma xenografts to treatment. ⺠Filamin-A is a cytoskeleton protein that supports DNA repair. ⺠Filamin-A may be used as a biomarker and target for DNA damage based cancer therapy.
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Authors
Jingyin Yue, Huimei Lu, Jingmei Liu, Marianne Berwick, Zhiyuan Shen,