| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1980681 | DNA Repair | 2011 | 11 Pages |
Abstract
⺠Mitotic growth arrest by PJ34 is PARP1 + 2 independent. ⺠PJ34 growth arrest occurs in cells from diverse genetic backgrounds. ⺠PJ34 causes a G2/M growth arrest, independent of ATM, p53 or Chk1. ⺠PJ34 growth arrest is caffeine sensitive and UCN01 insensitive. ⺠ATR is necessary for PJ34 growth arrest. ⺠PJ34 activates p21 gene expression by both p53 dependent and independent pathways.
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Authors
Dana L. Madison, Daniel Stauffer, James R. Lundblad,