Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1980708 | DNA Repair | 2008 | 11 Pages |
Abstract
The widespread but differential expression of the DNA glycosylases recognizing oxidative base lesions suggests distinct and age dependent roles of these enzymes in genome maintenance in brain. The distribution of mNeil3 is particularly intriguing and points to a specific role of this enzyme in stem cell differentiation.
Keywords
NEILpostnatal day 3NthTCrRMSBEREndonuclease IIISVZ8-oxoG2,6-diamino-4-hydroxy-5-formamidopyrimidine8-oxoguanineapurinic/apyrimidinicIn situ hybridizationROSDARHumanGGRTranscription-coupled repairbase excision repairGlobal genomic repairrostral migratory streamAgingCockayne syndromeFapysubventricular zoneMiceReactive oxygen species
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Authors
Veslemøy Rolseth, Elise Rundén-Pran, Luisa Luna, Cynthia McMurray, Magnar BjørÃ¥s, Ole Petter Ottersen,