Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1981544 | DNA Repair | 2006 | 4 Pages |
Abstract
SUMO is a small ubiquitin-like protein that is attached to target proteins, altering their localization and function. The condensin and cohesin-related Smc5/6 complex has been linked to DNA repair and checkpoint responses, but details of its molecular function have remained obscure. Recent reports show one subunit of the complex is a SUMO ligase, providing another link between protein sumoylation and DNA damage responses.
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Authors
Karen M. Lee, Matthew J. O’Connell,