Article ID Journal Published Year Pages File Type
1981544 DNA Repair 2006 4 Pages PDF
Abstract

SUMO is a small ubiquitin-like protein that is attached to target proteins, altering their localization and function. The condensin and cohesin-related Smc5/6 complex has been linked to DNA repair and checkpoint responses, but details of its molecular function have remained obscure. Recent reports show one subunit of the complex is a SUMO ligase, providing another link between protein sumoylation and DNA damage responses.

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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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