A new hybrid bacteriocin, Ent35-MccV, displays antimicrobial activity against pathogenic Gram-positive and Gram-negative bacteria

▸ A chimerical gene encoding a hybrid bacteriocin-microcin was generated by PCR. ▸ Ent35-MccV is a hybrid bacteriocin containing enterocin CRL35 and microcin V. ▸ Ent35-MccV is active against Gram-positive and Gram-negative bacteria. ▸ Enterohemorrhagic Escherichia coli and Listeria monocytogenes are sensitive to Ent35-MccV.