Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1983572 | The International Journal of Biochemistry & Cell Biology | 2013 | 10 Pages |
Abstract
- CK2 and PDX-1 shuttle glucose dependently from the cytosol into the nucleus.
- Glucose stimulates protein kinase activity of CK2.
- Glucose enhances binding of CK2 to PDX-1.
- CK2 is a co-factor of PDX-1 in the regulation of insulin production in β-cells.
Keywords
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Biochemistry
Authors
Sabrina Welker, Claudia Götz, Christina Servas, Matthias W. Laschke, Michael D. Menger, Mathias Montenarh,