| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1983938 | The International Journal of Biochemistry & Cell Biology | 2011 | 12 Pages |
Abstract
⺠The TvCP39 proteinase of Trichomonas vaginalis was identified using a proteomic approach. ⺠TvCP39 is encoded by a 915-bp cathepsin L-like cysteine proteinase gene (tvcp39). ⺠A recombinant TvCP39 mature fragment (TvCP39r) binds to the surface of HeLa cells and protects them from trichomonal destruction. ⺠TvCP39 is a glycosylated cysteine proteinase. ⺠The anti-TvCP39r antibody detects TvCP39 in vaginal secretions of patients with trichomonosis. ⺠TvCP39 is a potential biomarker for trichomonosis.
Keywords
vWSSNAfluorescein isothiocyanate conjugateECLNRSPNGase FIEFDAPIHGMCBBSambucus nigra agglutininTCADMEMIgGpeptide: N-glycosidase FcpsFITCBSACoomassie Brilliant BlueIPGimmobilized pH gradientDulbecco's modified Eagle's mediumbovine serum albumintrichloroacetic acidimmunoglobulin Aimmunoglobulin GIgATYMCon Aenhanced chemiluminescenceBiomarkerTrichomonas vaginalisELISAEnzyme-linked immunosorbent assayrapid amplification of cDNA endsisoelectric focusingheat-inactivated horse serumHIHSCytotoxicityRaceUTR یا untranslated regions untranslated regionNitrocelluloseWestern blotProteomicsCysteine proteinasecysteine proteinasesGlycoprotein
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Authors
Lucero de los Ángeles Ramón-Luing, Francisco Javier Rendón-Gandarilla, Jonathan Puente-Rivera, Leticia Ávila-González, Rossana Arroyo,