Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1985407 | The International Journal of Biochemistry & Cell Biology | 2007 | 9 Pages |
Abstract
These results allow us to conclude that activation/high expression of PKC-α protects parental drug-sensitive L1210 cells from iHDACs-mediated apoptosis. Thus, determination of PKC-α levels/activity in leukaemia seems to be relevant when choosing efficient chemotherapy protocols based on the use of apoptosis-inducing anticancer drugs.
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Biochemistry
Authors
MarÃa D. Castro-Galache, Maria P. Menéndez-Gutiérrez, Estefania Carrasco Garcia, Pilar Garcia-Morales, Isabel Martinez-Lacaci, Miguel Saceda, Jose A. Ferragut,