| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1986015 | International Journal of Biological Macromolecules | 2016 | 9 Pages |
Abstract
Chitosan-g-poly(acrylamide)/Zn (CPA-Zn) nanocomposite was synthesized using simple method in the presence of microwave radiations. CPA-Zn nanocomposite was characterized by various analytical techniques. CPA-Zn nanocomposite was used for controlled drug delivery of ofloxacin. The maximum drug release was 75% which was observed in acidic medium. The cumulative drug release and drug released kinetics of CPA-Zn was investigated. It was noticed that the drug release behavior depended upon the pH of medium as well as on the the nature of matrix. CPA-Zn nanocomposites were also studied for their antibacterial activity against E. coli bacteria.
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Authors
Deepak Pathania, Divya Gupta, N.C. Kothiyal, Gaurav sharma, G.E. Eldesoky, Mu. Naushad,