| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1986558 | International Journal of Biological Macromolecules | 2014 | 5 Pages |
Abstract
The alkali-extractable polysaccharide (AEP) was isolated from the root of North American ginseng. Two fractions, AEP-1 and AEP-2, were further purified by gel filtration column chromatography. Gas chromatography analysis identified that AEP-1 was composed of Glc, Gal and GalA. And AEP-2 mainly contained Ara, Man, Gal, Glc and GalA. Antioxidant assays indicated that AEP and AEP-2 exhibited significant antioxidant activities in a dose-dependent manner. AEP-2 also exhibited macrophage-activating activity by increasing NO, TNF-α and IL-6 production. The results suggest that AEP-2 could be used as potential antioxidants and immunomodulators.
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Authors
Xiaona Yu, Xiushi Yang, Bo Cui, Lijun Wang, Guixing Ren,