| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1987188 | International Journal of Biological Macromolecules | 2012 | 10 Pages |
Abstract
⺠A series of thiazolo-pyrazolyl derivatives were designed and synthesized. ⺠Derivatives Vq, Vo and Vh showed potent XO inhibitory and free radical scavenging activities. ⺠Docking highlights importance of Arg 880, Phe 914, Phe 1009, Leu 1011 and Phe 1013 residues for binding of inhibitor.
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Authors
Supriya D. Beedkar, Chandrahasya N. Khobragade, Santosh S. Chobe, Bhaskar S. Dawane, O.S. Yemul,