Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1987720 | International Journal of Biological Macromolecules | 2008 | 7 Pages |
Abstract
The temperature-responsive chitosan was synthesized by free radical polymerization of N-isopropylacrylamide (NIPAM) at 60 °C in the presence of RAFT-chitosan agent. The chitosan was subsequently modified with phthalic anhydride and with S-1-dodecyl-Sâ²-(α,αâ²-dimethyl-αâ³-acetic acid) trithiocarbonate to serve as reversible addition fragmentation chain transfer (RAFT) agent. The polymerization results show that the graft polymerization proceeded via RAFT process, while the “well-defined” graft polymers were successfully synthesized. The temperature played an important role on the self-assembly in H2O dispersion and the morphologies of chitosan-g-PNIPAMs. To our knowledge, this is the first thermosensitive chitosan prepared from controlled graft modification of chitosan by RAFT polymerization.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Jing Tang, Daoben Hua, Jianxin Cheng, Jing Jiang, Xiulin Zhu,