Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1988244 | International Journal of Biological Macromolecules | 2007 | 5 Pages |
Abstract
The interaction of a structurally characterized Sr–Fe nitrosyl complex with DNA has been studied by UV–vis and fluorescence spectroscopy, viscometric, and gel electrophoresis techniques. From the absorption titration studies the intrinsic binding constant of the complex with DNA was calculated to be 1.6 × 104 M−1. Fluorimetric studies indicate that the complex compete with EB in binding to DNA. The complex shows nuclease activity on pUC19 supercoiled DNA in presence of H2O2.
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Authors
Md Selim, Sujoy Roy Chowdhury, Kalyan K. Mukherjea,