Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1988937 | Journal of Chemical Neuroanatomy | 2013 | 14 Pages |
Abstract
⺠The hypothalamic sources of MCH-ir/NEI-ir inputs to the hippocampal formation are the periventricular nucleus, incerto-hypothalamic area, the lateral hypothalamic area and the supramammillary nucleus. ⺠The MCH-ir fibers make putative synapse contact to cholinergic cells in the medial septal nucleus which in turn sends out projections to the hippocampal formation. ⺠The MCH-ir fibers make putative synapse contact to GABAergic basket cells in the hippocampal formation. ⺠We propose that there are two pathways, one direct and the other indirect from hypothalamic sites to the hippocampal formation, and these would work as the pathways subserving the food-seeking behavior.
Keywords
LHADOPACBDACA2CA3KPBSCorpus callosumTBMORXAcbShMCHCARTPVHVMHD3VLepRbIHYDTAFNGEdichlorotriazinylaminofluoresceinSubIDABfluoro-goldSFOCA1PEFNASPAGFITCTrue bluecornu ammonis 3cornu Ammonis 1AChAcetylcholinearousalOrexincornu ammonis 2lateral ventriclethird ventriclebiotinylated dextran aminehippocampal formationSpatial memoryNEICNSmammillothalamic tractdiaminobenzidineMotivated behaviorBlood vesselcentral nervous systemdentate gyrusSubfornical organfluorescein isothiocyanatefornixFimbriaArcPeriaqueductal gray matterSUMfood intakelateral hypothalamic areaperifornical areaCholinergic neuronsSupramammillary nucleusVentromedial nucleus of the hypothalamusTuberomammillary nucleusmedial septal nucleusarcuate nucleus of the hypothalamusparaventricular nucleus of the hypothalamusperiventricular nucleusmelanin-concentrating hormonepotassium phosphate-buffered salineChATanterior commissurecholine acetyltransferaseGABAgamma-amino butyric acid
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Authors
Fernando F.B. Lima, Luciane V. Sita, Amanda R. Oliveira, Helder C. Costa, Joelcimar M. da Silva, Renato A. Mortara, Carlos A.S. Haemmerle, Gilberto F. Xavier, Newton S. Canteras, Jackson C. Bittencourt,