| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1988952 | Journal of Chemical Neuroanatomy | 2011 | 8 Pages |
Abstract
⺠cAMP signaling is important in several brain functions including pain transmission. ⺠The brain distribution of the cAMP hydrolyzing PDE8A remains to be investigated. ⺠PDE8A was located to neuronal perikaryal cytoplasm and extending processes. ⺠PDE8A was found in the forebrain, brain stem, cerebellum and trigeminal ganglion. ⺠PDE8A may be involved in pain transmission, motor function, cognition and olfaction.
Keywords
Nucleus Gracilispontine reticular nucleusIGSCPDE8VDBPBGIPNDLGMRNEPLFasciculus retroflexusHDBPAGOPTCA1AOPSTRICPSp5AmygdalaStriatumimmImmunohistochemistryPirSpinal trigeminal tractsubstantia nigraperiaqueductal grayPainMamillothalamic tractoptic tractSuperior colliculusinferior cerebellar pedunclearea postremaPosteriorPhosphodiesteraseMotor cortexpiriform cortexlateral olfactory tractLarBraininterpeduncular nucleusParabigeminal nucleusReticular nucleusSolitary nucleusinferior olivary nucleusanterior olfactory nucleusventral cochlear nucleuslateral reticular nucleusspinal trigeminal nucleusmedial septal nucleusred nucleusGigantocellular reticular nucleusdorsal cochlear nucleusochPARsoptic chiasmPosterior commissureinternal capsuletrigeminal ganglionGlobus pallidusIon
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Authors
Lars Schack Kruse, Morten Møller, Christina Kruuse,