| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1988965 | Journal of Chemical Neuroanatomy | 2011 | 14 Pages |
Abstract
⺠Relaxin-3 gene encodes a conserved neuropeptide in mammals and lower species. ⺠GPCR135 or RXFP3 is the native G-protein coupled receptor for relaxin-3. ⺠Relaxin-3 is expressed in brainstem GABA neurons that project broadly to forebrain. ⺠Relaxin-3 neural network is hypothesised to represent an ascending arousal system. ⺠Relaxin-3/RXFP3 signalling has putative roles in arousal, stress, mood and memory.
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Authors
Craig M. Smith, Philip J. Ryan, Ihaia T. Hosken, Sherie Ma, Andrew L. Gundlach,