Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1988993 | Journal of Chemical Neuroanatomy | 2012 | 11 Pages |
Abstract
⺠Cellular prion protein (PrPc) could have a neuroprotective role against apoptosis. ⺠Studies were performed on cerebellar vermis sections after Pt compounds treatment. ⺠Co-localization of PrPc, Bcl-2 and Bax arose from differentiating Purkinje cells. ⺠PrPc, together with Bcl-2 action, limited cytotoxicity during postnatal development.
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Authors
Maria Grazia Bottone, Veronica Dal Bo, Valeria Maria Piccolini, Giovanni Bottiroli, Sandra Angelica De Pascali, Francesco Paolo Fanizzi, Graziella Bernocchi,