Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1989027 | Journal of Chemical Neuroanatomy | 2012 | 5 Pages |
Abstract
⺠The protective effects of chlorogenic acid on methotrexate-induced cerebellar Purkinje cell injury were confirmed by histopathological analyses. ⺠Oxidative stress markers including malondialdehyde, superoxide dismutase, catalase and glutathione, in cerebellum were determined. ⺠The neuroprotective mechanism was discussed in the view of antioxidative system. ⺠Chlorogenic acid could be beneficial for prevention from the side-effects of chemotherapeutics.
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Authors
Nigar Vardi, Hakan Parlakpinar, Burhan Ates,