| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1991283 | The Journal of Steroid Biochemistry and Molecular Biology | 2016 | 6 Pages |
Abstract
Cell fate specification is a critical process to generate cells with a wide range of characteristics from stem and progenitor cells. Emerging evidence demonstrates that the orphan nuclear receptor COUP-TFII serves as a key regulator in determining the cell identity during embryonic development. The present review summarizes our current knowledge on molecular mechanisms by which COUP-TFII employs to define the cell fates, with special emphasis on cardiovascular and renal systems. These novel insights pave the road for future studies of regenerative medicine.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
San-Pin Wu, Cheng-Tai Yu, Sophia Y. Tsai, Ming-Jer Tsai,