| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1991602 | The Journal of Steroid Biochemistry and Molecular Biology | 2012 | 9 Pages |
Abstract
⺠3α-Hydroxysteroid dehydrogenase (3α-HSD/CR) initiates steroid degradation in Comamonas testosteroni. ⺠The gene coding for 3α-HSD/CR, hsdA, is regulated by multiple factors including HsdR. ⺠HsdR belongs to the LysR-type transcriptional regulator (LTTR) family. ⺠Interestingly, HsdR is active as an oligomer in the regulation of hsdA expression. ⺠Further, HsdR negatively regulates its own expression.
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Authors
Wenjie Gong, Guangming Xiong, Edmund Maser,