Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1992076 | The Journal of Steroid Biochemistry and Molecular Biology | 2008 | 10 Pages |
Abstract
These results demonstrate that androgen-independent tumors contain androgen-responsive cells. The apparent discrepancy between the responses to androgen of tumors and those of carcinoma cells in culture suggests that microenvironmental factors contribute to the androgen responsiveness of tumor cells in vivo. These modifications, albeit unspecified, could be suitable targets for restoring the androgen responsiveness of AI tumors.
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Authors
Marie-Odile Joly-Pharaboz, Jean-Jacques Kalach, Julie Pharaboz, Jacqueline Chantepie, Brigitte Nicolas, Marie-Laurence Baille, Alain Ruffion, Mohamed Benahmed, Jean André,