| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1994454 | Methods | 2006 | 5 Pages |
Abstract
Knowing the genomic distribution of chromosomal proteins and of histone modifications provides essential insight into function. The giant polytene chromosomes of the Drosophila larval salivary glands provide a high-resolution genomic map with a resolution exceeded only by chromatin immunoprecipitation. Immunofluorescence localization of chromosomal proteins and specific post-translational modifications of histones is a simple and rapid tool for the functional genomics of chromosomal proteins.
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Authors
Joel C. Eissenberg,