Rapamycin reduces high-amplitude, mechanical stretch-induced apoptosis in pulmonary microvascular endothelial cells

Article ID	Journal	Published Year	Pages	File Type
1995386	Microvascular Research	2009	7 Pages	PDF

Abstract

According to the data from the present study, rapamycin represents a promising cytoprotective agent under mechanically challenging conditions such as mechanical ventilation.

Keywords

HMVEC-L PBS ARDS mTOR FCS Acute lung injury Ventilator-induced lung injury lactic acid dehydrogenase Ali fetal calf serum Alveolar type II cell Acute respiratory distress syndrome Phosphate buffered saline LDH Cell death mammalian target of rapamycin VILI Propidium iodide Cytoskeleton Mechanical stretch