| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1995926 | Molecular Aspects of Medicine | 2008 | 7 Pages |
Abstract
Protein kinase C (PKC) is a family of isoenzymes differently involved in cell response to injury and many studies describe their role as “stress sensors”. Oxidative stress is strictly involved in the pathogenesis of chronic liver diseases including alcohol- or drug-induced hepatotoxicity, iron overload, hepatitis and hepatocarcinoma development, but molecular mechanisms are not really defined. A crucial role of PKC as a redox sensitive signaling molecule has been widely accepted.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Mariapaola Nitti, Maria A. Pronzato, Umberto M. Marinari, Cinzia Domenicotti,