| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1996286 | Molecular Cell | 2013 | 12 Pages |
Abstract
⺠A Cdt1 interaction with MCM2-7 alleviates an autoinhibitory activity in Mcm6 ⺠OCM establishment occurs fast, while MCM2-7 double-hexamer formation is slow ⺠Both Orc1 and Cdc6 ATP-hydrolysis promote Cdt1 release and OCM formation ⺠The OCM represents a platform for double-hexamer assembly
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Authors
Alejandra Fernández-Cid, Alberto Riera, Silvia Tognetti, M. Carmen Herrera, Stefan Samel, Cecile Evrin, Christian Winkler, Emanuela Gardenal, Stefan Uhle, Christian Speck,