Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1996586 | Molecular Cell | 2012 | 11 Pages |
Abstract
⺠Sirt1 interacts with both USP22 and p53 to form a complex ⺠USP22 is a deubiquitinase of Sirt1 ⺠USP22 inhibits p53 functions through Sirt1 stabilization ⺠Targeted usp22 gene mutation leads to mouse embryonic lethality
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Zhenghong Lin, Heeyoung Yang, Qingfei Kong, Jinping Li, Sang-Myeong Lee, Beixue Gao, Hongxin Dong, Jianjun Wei, Jianxun Song, Donna D. Zhang, Deyu Fang,