Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1996701 | Molecular Cell | 2010 | 10 Pages |
Abstract
⺠Promiscuity in amino acid modification allows Hrd1 to recognize numerous ER proteins ⺠Hrd1 required for Ub conjugation not only on lysines but also on serines/threonines ⺠Hrd1-mediated ubiquitin chain elongation is via conventional isopeptide linkages ⺠Mutation of K, S, and T residues is required to inhibit Ub and stabilize NS-1 LC
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Authors
Yuichiro Shimizu, Yuki Okuda-Shimizu, Linda M. Hendershot,