| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1997148 | Molecular Cell | 2012 | 11 Pages |
Abstract
⺠HDAC4 targets the AP1 but not MEF2 transcription program in neurogenic muscle atrophy ⺠HDAC4 stimulates AP1 activity by activating MAP kinase signaling ⺠HDAC4 activates the MAPK cascade by promoting the deacetylation a MAP3K, MEKK2 ⺠The HDAC4-MAPK-AP1 signaling cascade is essential for neurogenic muscle atrophy
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Authors
Moon-Chang Choi, Todd J. Cohen, Tomasa Barrientos, Bin Wang, Ming Li, Bryan J. Simmons, Jeong Soo Yang, Gregory A. Cox, Yingming Zhao, Tso-Pang Yao,