Article ID Journal Published Year Pages File Type
1999616 Molecular Genetics and Metabolism 2007 4 Pages PDF
Abstract

Mice with deletion of the galactose-1-phosphate uridyltransferase (GALT) gene were examined for their ability to form 13C labeled hepatic UDP glucose from administered 1-13C galactose. NMR analysis of urinary acetaminophen glucuronide, which is derived from hepatic UDP glucose showed 13C enrichment after concomitant administration of 13C galactose and acetaminophen. The finding is consistent with the function of UDP galactose pyrophosphorylase as an alternate pathway of galactose metabolism.

Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , ,