Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2001372 | Nitric Oxide | 2012 | 11 Pages |
Abstract
⺠Caveolin-1/eNOS interaction is essential preventing inadequate NO levels. ⺠Rosuvastatin treatment can afford protection against fibrosis induction during neonatal UUO. ⺠Interstitial fibrosis was associated with Cav-1 up-regulation, reduced NO levels and decreased eNOS/Hsp70 interaction. ⺠NO availability involves protein-protein interaction of up-regulated eNOS/Hsp70 and down-regulated caveolin-1.
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Authors
Isabel Mercedes GarcÃa, Luciana Mazzei, MarÃa Eugenia Benardón, Liliana Oliveros, Fernando DarÃo Cuello-Carrión, Andrea Gil Lorenzo, Walter Manucha, Patricia G. Vallés,