Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2006208 | Peptides | 2013 | 9 Pages |
Abstract
- Hsp70(241-258), a partial sequence of heat shock protein derived from rice, is a novel cationic α-helical peptide.
- Hsp70(241-258) exhibited antimicrobial activity against Porphyromonas gingivalis and Candida albicans.
- The IC50 values were 63 μM and 70 μM for P. gingivalis and C. albicans, respectively.
- Hsp70(241-258) has neither hemolytic activity nor cytotoxicity.
- Hsp70(241-258) appears to exhibited antimicrobial activity through disruption of cell membranes.
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Authors
Masayuki Taniguchi, Atsuo Ikeda, Shun-ichi Nakamichi, Yohei Ishiyama, Eiichi Saitoh, Tetsuo Kato, Akihito Ochiai, Takaaki Tanaka,