| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2006268 | Peptides | 2012 | 9 Pages |
Abstract
⺠Compelling evidence now exists for complete, independent, differentially regulated intracellular renin-angiotensin systems in many tissues. ⺠Angiotensinogen, the enzymes renin and angiotensin converting enzyme and angiotensin peptides can be synthesized and retained intracellularly. ⺠Angiotensin receptors (AT1 and AT2) are abundant intracellularly mainly at the nuclear and mitochondrial levels. ⺠Functional intracellular renin-angiotensin system units have been documented both in nuclei and mitochondria.
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Authors
Peter M. Abadir, Jeremy D. Walston, Robert M. Carey,